Diabetologia 2000;43(3):294-303. High levels of fats called triglycerides in the blood (hypertriglyceridemia). a-lipoic acid in patients with autosomal dominant polycystic kidney disease. Alpha-lipoic acid … Ter Arkh 2010;82(12):61-64. Oral administration of RAC-alpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled, pilot trial. 2005;77(10):15-19. Gurer H, Ozgunes H, Oztezcan S, Ercal N. Antioxidant role of alpha-lipoic acid in lead toxicity. As discussed earlier, alpha lipoic acid is known to lower blood sugar levels, making it suitable for diabetic patients. Karaarslan U, Isgüder R, Bag Ö, et al. View abstract. J Pediatr 1984;104:65-9. Lipoic acid (also known as alpha lipoic acid) is an antioxidant available as an over-the-counter supplement taken by people with a variety of conditions, including HIV and diabetes. Ophthalmologica 2011;226(3):127-137. Free Radic.Biol.Med 2000;29(11):1122-1128. JAMA 10-7-2009;302(13):1451-1458. View abstract. A., Rubin, D. I., and Demaerschalk, B. M. Alpha-lipoic acid may improve symptomatic diabetic polyneuropathy. This survey is being conducted by the WebMD marketing sciences department. Lopez-D'alessandro E., Escovich L. Combination of alpha lipoic acid and gabapentin, its efficacy in the treatment of Burning Mouth Syndrome: a randomized, double-blind, placebo controlled trial. Int J Angiol. Early research suggests that taking a product containing alpha-lipoic acid and other ingredients starting 8 weeks before UV phototherapy and continuing during phototherapy treatment increases the effectiveness of phototherapy in people with skin discoloration characterized by white patches. 2017 Aug;41(4):275-83. Chaparro, L. E., Wiffen, P. J., Moore, R. A., and Gilron, I. Support Care Cancer 2014;22(5):1223-31. Lee, S. H., Kim, M. J., Kim, B. J., Kim, S. R., Chun, S., Ryu, J. S., Kim, G. S., Lee, M. C., Koh, J. M., and Chung, S. J. Homocysteine-lowering therapy or antioxidant therapy for bone loss in Parkinson's disease. Alpha-lipoic acid. There are a lot of foods that contain alpha lipoic acid naturally, but the levels are very low. Attenuation of aminoglycoside-induced cochlear damage with the metabolic antioxidant alpha-lipoic acid. Filina A. Maesaka H, Komiya K, Misugi K, Tada K. Hyperalaninemia hyperpyruvicemia and lactic acidosis due to pyruvate carboxylase deficiency of the liver; treatment with thiamine and lipoic acid. Taking alpha-lipoic acid along with diabetes medications might cause your blood sugar to go too low. Examples of foods that you may want to add for your diet include rice bran, beets, carrots, Brussels sprouts, tomatoes, potatoes, yams, broccoli, and spinach. Cavestro C, Bedogni G, Molinari F, Mandrino S, Rota E, Frigeri MC. Hormones.(Athens.) Fruzzetti F, Benelli E, Fidecicchi T, et al. Lee SJ, Jeong SJ, Lee YC, et al. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Early research suggests that taking alpha-lipoic acid plus superoxide dismutase daily for 2 months reduces chronic neck pain when used along with physiotherapy. J Int Med Res 2005;33(3):267-272. View abstract. Diabet Care 1995;18:1160-7. Clin Sci (Lond) 2009;116(5):433-441. Mijnhout, G. S., Alkhalaf, A., Kleefstra, N., and Bilo, H. J. Alpha lipoic acid: a new treatment for neuropathic pain in patients with diabetes? Ziegler D, Nowak H, Kempler P, et al. 2008;2:49-50. View abstract. B., Bates M. G., Sutherland A. I., Macnee W., Maxwell S. R., Webb D. J. Alpha-lipoic acid (LA) possesses beneficial effects both in the prevention and in the treatment of diabetes. Janson, M. Orthomolecular medicine: the therapeutic use of dietary supplements for anti-aging. J Med Food. Biochem Pharmacol 5-18-1994;47(10):1725-1730. Diabet Med 1999;16:1040-3. View abstract. A-Lipoic Acid, Acetate Replacing Factor, Acide Alpha-Lipoïque, Acide Alpha-Lipoïque R, Acide DL-Alpha-Lipoïque,Acide Lipoïque, Acide Thioctique, Acide 1,2-dithiolane-3-pentanoïque, Acide 1,2-dithiolane-3-valérique, Acide 5 Valérique (1,2-dithiolan-3-yl), Acide 6,8-dithiooctanoïque, Acide 6,8-Thioctique, Acido Alfa Lipoico, ALA, Biletan, DHLA, Extrait d'acide Alpha-Lipoïque, Lipoic Acid, Lipoicin, R-ALA, R-Alpha-Lipoic Acid, (+-)-1,2-Dithiolane-3-Pentanoic Acid, (R)-Dithiolane-3-Pentanoic Acid,R, S-Alpha Lipoic Acid, (R)-Lipoic Acid, R-Lipoic Acid, RS-Alpha-Lipoic Acid, S-Alpha-Lipoic Acid, S-Lipoic Acid, Sodium-R-Lipoate, Thioctacid, Thioctan,Thioctic Acid. Zembron-Lacny, A., Slowinska-Lisowska, M., Szygula, Z., Witkowski, K., Stefaniak, T., and Dziubek, W. Assessment of the antioxidant effectiveness of alpha-lipoic acid in healthy men exposed to muscle-damaging exercise. To avoid any interactions … LA in the diet is quickly absorbed, transported to the intracellular compartments, and reduced to dihydrolipoic acid (DHLA) under the action of enzymes. Korkina L. G., Afanas'ef I. Arzneimittelforschung 1995;45:872-4. Early research shows that taking alpha-lipoic acid does not help to prevent this recurrence. Hegazy SK, Tolba OA, Mostafa TM, Eid MA, El-Afify DR. Alpha-lipoic acid improves subclinical left ventricular dysfunction in asymptomatic patients with type 1 diabetes. Neck pain. It may have several health benefits. Packer L, Tritschler HJ, Wessel K. Neuroprotection by the metabolic antioxidant alpha-lipoic acid. Shanghai Medical Journal 2008;31:364-365. Effects of shuxuening and -lipoic acid on diabetic peripheral neuropathy. Mantovani, G., Maccio, A., Madeddu, C., Gramignano, G., Lusso, M. R., Serpe, R., Massa, E., Astara, G., and Deiana, L. A phase II study with antioxidants, both in the diet and supplemented, pharmaconutritional support, progestagen, and anti-cyclooxygenase-2 showing efficacy and safety in patients with cancer-related anorexia/cachexia and oxidative stress. Kucukgoncu S, Zhou E, Lucas KB, Tek C. Alpha-lipoic acid (ALA) as a supplementation for weight loss: results from a meta-analysis of randomized controlled trials. Haak E., Usadel K. H., Kusterer K., Amini P., Frommeyer R., Tritschler H. J., Haak T. Effects of alpha-lipoic acid on microcirculation in patients with peripheral diabetic neuropathy. Am J Physiol Heart Circ.Physiol 2009;297(5):H1870-H1875. Berkson, B. M., Rubin, D. M., and Berkson, A. J. Revisiting the ALA/N (alpha-lipoic acid/low-dose naltrexone) protocol for people with metastatic and nonmetastatic pancreatic cancer: a report of 3 new cases. Medically reviewed by Drugs.com on June 8, 2020. Mittermayer, F., Pleiner, J., Francesconi, M., and Wolzt, M. Treatment with alpha-lipoic acid reduces asymmetric dimethylarginine in patients with type 2 diabetes mellitus. A meta-analysis and systematic review on randomized controlled trials. In addition, many alternative practitioners contend that alpha-lipoic acid can prevent or treat a multitude of health conditions, including alcoholic liver disease, HIV, Alzheimer's disease, bipolar disorder, cardiac arrhythmia, high blood pressure, rheumatoid arthritis, premature labor, schizoph… Zhao YY. Alpha-Lipoic Acid | Memorial Sloan Kettering Cancer Center MSK is now offering COVID-19 vaccine to patients age 65 and over who live in New York State and are in active treatment with … Volchegorskii I. Alpha lipoic acid, or ALA, is a type of antioxidant. 2020;11:131-139. Bangma, H. R., Smit, G. P., Kuks, J. Early research suggests that taking alpha-lipoic acid alone or together with vitamin E for 28 days might reduce symptoms of radiation exposure in children living near areas contaminated with radiation. Alpha-lipoic acid blocks HIV-1 LTR-dependent expression of hygromycin resistance in THP-1 stable transformants. Investigations on the pharmacokinetics of alpha-lipoic acid in healthy volunteers. Gynecol Endocrinol. Effect of Alpha-lipoic acid amide on hexachlorobenzene porphyria. View abstract. We comply with the HONcode standard for trustworthy health information -. Do not take alpha-lipoic acid without medical advice if you are using any of the following medications: medicines to treat underactive thyroid, such as levothyroxine (Synthroid) and others; or. Conditions in a man that prevent him from getting a woman pregnant within a year of trying to conceive (male infertility). Version: 3.02. multivitamin, biotin, ascorbic acid, calcium / vitamin d, Fish Oil. Healthy sperm have a better chance of fertilizing the egg, resulting in pregnancy. Minerva Stomatol. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. View abstract. Femiano F., Gombos F., Scully C., Busciolano M., Luca P. D. Burning mouth syndrome (BMS): controlled open trial of the efficacy of alpha-lipoic acid (thioctic acid) on symptomatology. Altern Med Rev 1998;3:308-10. Desideri I, Francolini G, Becherini C, et al. Consult with a licensed healthcare professional before using any herbal/health supplement. Neuropathy -- choices of treatment with oral lipoic acid ( berlition ) in diabetic. Consult with a type of irregular heartbeat can start again sardu C Bedogni. Oral treatment with oral lipoic acid alpha lipoic acid human immunodeficiency virus infected patients E1 on diabetic peripheral neuropathy a! 136 ( 10 ):859-69 sciences department Sci 2009 ; 116 ( 5 ).... 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